Recent research from Washington University in St. Louis suggests that dietary fructose may encourage tumor growth in certain cancers, based on animal model studies.
Fructose, a natural sugar present in fruits, some vegetables, and honey, is typically not harmful when consumed from these sources. However, its role changes when found in high-fructose corn syrup within processed foods. Overconsumption of such sweeteners has been associated with various health issues, including cancer.
Dr. Gary Patti from Washington University highlighted that the consumption of fructose has increased as it has become a common artificial sweetener in processed foods. This rise prompts exploration of its effects on health. Patti’s recent study published in Nature investigates how fructose may promote tumor growth in animal models of melanoma, breast cancer, and cervical cancer.
The study draws parallels between glucose and fructose. Cancer cells, known for their high glucose uptake, might similarly use fructose, given that both sugars consist of the same atoms, albeit arranged differently. Researchers found that when animals consumed a high-fructose diet, it led to an increase in lysophosphatidylcholines (LPCs)—lipids associated with inflammation—contributing to cancer cell replication and tumor growth.
In examining these effects, Patti explained that fructose is converted into lipids by the liver. These lipids can nourish rapidly dividing cancer cells, facilitating tumor development. This relationship underscores the substantial nutrients cancer cells require to proliferate, often sourced from dietary intake.
Dr. Anton Bilchik, a surgical oncologist, noted the persistent suspicion that processed foods, particularly those containing high-fructose corn syrup, correlate with rising cancer rates, especially among younger individuals. Though not involved in the study, Bilchik acknowledged its contribution to understanding the mechanisms by which fructose might influence cancer risk.
Nutritionist Monique Richard provided practical advice on minimizing fructose intake. She suggests choosing natural fruits instead of processed alternatives and emphasizes the importance of knowing the sugar contents in food by reading labels. Richard warns that many processed products labeled without high-fructose corn syrup might still contain other forms of sugar at high levels.
While moving away from any obsessive avoidance of processed foods, including those high in fructose, maintaining a balanced diet focused on natural ingredients is vital. This dietary shift supports healthier living by reducing risks associated with excessive fructose consumption.
As research continues, understanding how dietary choices impact cancer risk is crucial. The potential link between fructose consumption and tumor growth invites further study, encouraging informed dietary decisions.
Source: Medicalnewstoday
