Executive Summary
The Story So Far
Why This Matters
Who Thinks What?
Internationally renowned molecular materials chemist and oncologist Lin Wenbin has left the University of Chicago to join Westlake University in Hangzhou, China. Lin, a pioneering figure in the field of metal-organic frameworks (MOFs)—a chemistry area recognized with a Nobel Prize this year—confirmed his early retirement from the U.S. institution on Friday to take up a full-time position in eastern China.
A Distinguished Scientific Career
Lin Wenbin is celebrated for his exceptional contributions across chemistry, chemical biology, and oncology. Prior to his move, he served as the James Franck professor of chemistry at the University of Chicago, where he was also affiliated with its department of radiation and cellular oncology since 2013.
His work has been particularly impactful in the development of cutting-edge cancer treatments. Lin’s laboratory in Chicago is credited with originating the only two MOFs currently in clinical development worldwide, both aimed at cancer therapy.
Innovations in Cancer Treatment
One of the MOF-based treatments developed by Lin’s team is designed to enable more targeted and lower-dose X-ray delivery for radiotherapy. This innovation seeks to enhance treatment effectiveness while minimizing harm to patients and simultaneously activating the immune system to combat cancer cells.
The second therapeutic approach focuses on improving cancer immunotherapy. It utilizes photosensitizers embedded in drug particles, which are activated by X-rays or near-infrared light upon reaching a target tumor. This activation produces reactive oxygen species, which are then used to destroy cancerous cells.
New Role at Westlake University
At Westlake University, Lin Wenbin will serve as a full-time chair professor and head of the science school’s molecular materials laboratory for sustainable development and human health. Additionally, he will hold part-time positions within the university’s medical and engineering schools.
Broader Implications
Lin’s move underscores a broader trend of Chinese scientists returning from the United States to institutions within China. His relocation brings significant expertise and ongoing research in advanced molecular materials and cancer therapeutics to Westlake University, potentially bolstering China’s scientific research landscape.
